Chemotherapy- and Cancer-Related Nausea and Vomiting

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Chemotherapy- and cancer-related nausea and vomiting

Approximately one half of cancer patients will experience nausea or vomiting during the course of their disease either because of the cancer itself or because of their treatment. Emesis attributable to cancer warrants a careful investigation to determine whether a treatable underlying cause is responsible. Interventions using dexamethasone and octreotide may reduce vomiting attributable to bowe...

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Chemotherapy-Related Nausea and Vomiting and Treatment-Related Nausea and Vomiting

The intrinsic emetogenicity of an individual chemotherapy agent appears to be the most important predictive factor for the development of CINV, though CINV is also influenced by patient characteristics. Such characteristics include gender, age, and history of alcohol consumption (3). In addition, experiencing nausea and vomiting with prior chemotherapy is also a risk factor. Consistently, women...

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Chemotherapy-induced nausea and vomiting.

younger patient age, platinumor anthracyclinebased chemotherapy, low alcohol consumption, earlier cycles of chemotherapy, previous history of morning sickness, and prior emetic episodes after chemotherapy. The acute and delayed scoring systems both had good predictive accuracy when applied to the external validation sample (acute— auroc: 0.69; 95% confidence interval: 0.59 to 0.79; delayed—auro...

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Chemotherapy-induced nausea and vomiting.

Chemotherapy-induced nausea and vomiting (CINV) affects many cancer patients and has a great influence on quality of life. CINV involves coordination of several organs of the gastrointestinal tract, the peripheral and central nervous systems. Many neurotransmitters are involved in this process, and the predominant receptors are serotonin, neurokinin-1 and dopamine receptors. Risk factors for CI...

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Chemotherapy-Induced Nausea and Vomiting

In the past two decades, significant advances have been made in the management of chemotherapy-induced nausea and vomiting (CINV). These advances are primarily due to a greater understanding of the physiological and molecular pathways underlying CINV, which resulted in major progress in the management of patients with CINV. In the early 1990s, CINV treatment consisted of dex-amethasone [1]. Imp...

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ژورنال

عنوان ژورنال: Current Oncology

سال: 2008

ISSN: 1718-7729

DOI: 10.3747/co.2008.171